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Maximum inflation of the type 1 error rate when sample size and allocation rate are adapted in a pre-planned interim look.()

We calculate the maximum type 1 error rate of the pre-planned conventional fixed sample size test for comparing the means of independent normal distributions (with common known variance) which can be yielded when sample size and allocation rate to the treatment arms can be modified in an interim ana...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Graf, Alexandra C., Bauer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836563/
https://ncbi.nlm.nih.gov/pubmed/21495058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4230
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