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Sample size re-assessment leading to a raised sample size does not inflate type I error rate under mild conditions

BACKGROUND: One major concern with adaptive designs, such as the sample size adjustable designs, has been the fear of inflating the type I error rate. In (Stat Med 23:1023-1038, 2004) it is however proven that when observations follow a normal distribution and the interim result show promise, meanin...

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Detalhes bibliográficos
Autor principal: Broberg, Per
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738874/
https://ncbi.nlm.nih.gov/pubmed/23870495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-13-94
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