Nalaganje...
J chain synthesis and secretion of hexameric IgM is differentially regulated by lipopolysaccharide and interleukin 5.
Two functional polymeric forms of IgM can be produced by antibody-secreting B cells. Hexameric IgM lacks detectable J (joining) chain and activates complement 17-fold better than pentameric IgM, which usually contains one J chain per pentamer. Using the inducible B-cell lymphoma CH12, we determined...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1992
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC48365/ https://ncbi.nlm.nih.gov/pubmed/1736312 |
| Oznake: |
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