Analysis of CpG suppression in methylated and nonmethylated species.
The development of nearest-neighbor analysis led to the finding that the frequency of the dinucleotide CpG is markedly depressed in vertebrates. One explanation of this suppression is that methylation of CpG found in vertebrates represents a mutational hot spot through deamination of methylcytidine...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1736311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.3.957 |
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