Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z

The arenavirus matrix protein Z is highly multifunctional and occurs in both monomeric and oligomeric forms. The crystal structure of a dodecamer of Z from Lassa virus, presented here, illustrates a ring-like structure with a highly basic center. Mutagenesis demonstrates that the dimeric interface w...

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Vydáno v:J Virol
Hlavní autoři: Hastie, Kathryn M., Zandonatti, Michelle, Liu, Tong, Li, Sheng, Woods, Virgil L., Saphire, Erica Ollmann
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836352/
https://ncbi.nlm.nih.gov/pubmed/26912609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02896-15
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