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APOBEC3G and APOBEC3F Act in Concert To Extinguish HIV-1 Replication

The multifunctional HIV-1 accessory protein Vif counters the antiviral activities of APOBEC3G (A3G) and APOBEC3F (A3F), and some Vifs counter stable alleles of APOBEC3H (A3H). Studies in humanized mice have shown that HIV-1 lacking Vif expression is not viable. Here, we look at the relative contribu...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Krisko, John F., Begum, Nurjahan, Baker, Caroline E., Foster, John L., Garcia, J. Victor
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836340/
https://ncbi.nlm.nih.gov/pubmed/26912618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03275-15
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