Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover

Cardiotrophin-like cytokine:cytokine-like factor-1 (CLC:CLF-1) is a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development. Mice lacking CLC:CLF-1 die soon after birth due to a suckling defect and show reduced numbers of motor neurons. Humans carrying mutations in C...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Larsen, Jakob Vejby, Kristensen, Anders Mejer, Pallesen, Lone Tjener, Bauer, Johannes, Vægter, Christian Bjerggaard, Nielsen, Morten Schallburg, Madsen, Peder, Petersen, Claus Munck
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836274/
https://ncbi.nlm.nih.gov/pubmed/26858303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00917-15
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