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Is There Potential to Target FOXM1 for “Undruggable” Lung Cancers?
Published studies with transgenic mice convincingly showed that FOXM1 transcription factor is an important component of the KRAS/ERK signaling pathway in respiratory epithelial cells. FOXM1 is required for oncogenic KRAS signaling in mouse lung cancer models and therefore, clear potential exists to...
Shranjeno v:
| izdano v: | Expert Opin Ther Targets |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836176/ https://ncbi.nlm.nih.gov/pubmed/25936405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2015.1042366 |
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