Autophagy-mediated longevity is modulated by lipoprotein biogenesis

Autophagy-dependent longevity models in C. elegans display altered lipid storage profiles, but the contribution of lipid distribution to life-span extension is not fully understood. Here we report that lipoprotein production, autophagy and lysosomal lipolysis are linked to modulate life span in a co...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Seah, Nicole E., de Magalhaes Filho, C. Daniel, Petrashen, Anna P., Henderson, Hope R., Laguer, Jade, Gonzalez, Julissa, Dillin, Andrew, Hansen, Malene, Lapierre, Louis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836030/
https://ncbi.nlm.nih.gov/pubmed/26671266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1127464
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