Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer

LAMP2A is the key protein of chaperone-mediated autophagy (CMA), downregulation of LAMP2A leads to CMA blockade. CMA activation has been implicated in cancer growth, but the exact mechanisms are unclear. Elevated expression of LAMP2A was found in 8 kinds of tumors (n=747), suggesting that LAMP2A may...

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Enregistré dans:
Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Zhou, Jinfeng, Yang, Jianjun, Fan, Xing, Hu, Sijun, Zhou, Fenli, Dong, Jiaqiang, Zhang, Song, Shang, Yulong, Jiang, Xiaoming, Guo, Hao, Chen, Ning, Xiao, Xiao, Sheng, Jianqiu, Wu, Kaichun, Nie, Yongzhan, Fan, Daiming
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Basic Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836009/
https://ncbi.nlm.nih.gov/pubmed/26761524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1136770
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