Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer

LAMP2A is the key protein of chaperone-mediated autophagy (CMA), downregulation of LAMP2A leads to CMA blockade. CMA activation has been implicated in cancer growth, but the exact mechanisms are unclear. Elevated expression of LAMP2A was found in 8 kinds of tumors (n=747), suggesting that LAMP2A may...

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Vydáno v:Autophagy
Hlavní autoři: Zhou, Jinfeng, Yang, Jianjun, Fan, Xing, Hu, Sijun, Zhou, Fenli, Dong, Jiaqiang, Zhang, Song, Shang, Yulong, Jiang, Xiaoming, Guo, Hao, Chen, Ning, Xiao, Xiao, Sheng, Jianqiu, Wu, Kaichun, Nie, Yongzhan, Fan, Daiming
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836009/
https://ncbi.nlm.nih.gov/pubmed/26761524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1136770
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