Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer

LAMP2A is the key protein of chaperone-mediated autophagy (CMA), downregulation of LAMP2A leads to CMA blockade. CMA activation has been implicated in cancer growth, but the exact mechanisms are unclear. Elevated expression of LAMP2A was found in 8 kinds of tumors (n=747), suggesting that LAMP2A may...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhou, Jinfeng, Yang, Jianjun, Fan, Xing, Hu, Sijun, Zhou, Fenli, Dong, Jiaqiang, Zhang, Song, Shang, Yulong, Jiang, Xiaoming, Guo, Hao, Chen, Ning, Xiao, Xiao, Sheng, Jianqiu, Wu, Kaichun, Nie, Yongzhan, Fan, Daiming
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836009/
https://ncbi.nlm.nih.gov/pubmed/26761524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1136770
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