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Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging

Regeneration of skeletal muscle relies on its resident stem cells, also known as satellite cells, which are normally quiescent. With aging, satellite cell quiescence is lost concomitant with a muscle regenerative decline. Here we demonstrate that autophagy sustains quiescence over time and that its...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: García-Prat, Laura, Muñoz-Cánoves, Pura, Martinez-Vicente, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835950/
https://ncbi.nlm.nih.gov/pubmed/26890313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1143211
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