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Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging

Regeneration of skeletal muscle relies on its resident stem cells, also known as satellite cells, which are normally quiescent. With aging, satellite cell quiescence is lost concomitant with a muscle regenerative decline. Here we demonstrate that autophagy sustains quiescence over time and that its...

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Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: García-Prat, Laura, Muñoz-Cánoves, Pura, Martinez-Vicente, Marta
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835950/
https://ncbi.nlm.nih.gov/pubmed/26890313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1143211
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