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ROMK inhibitor actions in the nephron probed with diuretics

Diuretics acting on specific nephron segments to inhibit Na(+) reabsorption have been used clinically for decades; however, drug interactions, tolerance, and derangements in serum K(+) complicate their use to achieve target blood pressure. ROMK is an attractive diuretic target, in part, because its...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Kharade, Sujay V., Flores, Daniel, Lindsley, Craig W., Satlin, Lisa M., Denton, Jerod S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835929/
https://ncbi.nlm.nih.gov/pubmed/26661652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00423.2015
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