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A mild reduction of food intake slows disease progression in an orthologous mouse model of polycystic kidney disease
Autosomal-dominant polycystic kidney disease (ADPKD) is a common cause of end-stage renal disease, and no approved treatment is available in the United States to slow disease progression. The mammalian target of rapamycin (mTOR) signaling pathway is aberrantly activated in renal cysts, and while mTO...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835927/ https://ncbi.nlm.nih.gov/pubmed/26764208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00551.2015 |
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