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Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis

Mechanisms of plasticity to acquire different cell fates are critical for adult stem cell (SC) potential, yet are poorly understood. Reduced global histone methylation is an epigenetic state known to mediate plasticity in cultured embryonic SCs and T-cell progenitors. Here we find histone H3 K4/K9/K...

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發表在:Nat Commun
Main Authors: Lee, Jayhun, Kang, Sangjo, Lilja, Karin C., Colletier, Keegan J., Scheitz, Cornelia Johanna Franziska, Zhang, Ying V., Tumbar, Tudorita
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835553/
https://ncbi.nlm.nih.gov/pubmed/27080563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11278
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