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Amplicon-based semiconductor sequencing of human exomes: performance evaluation and optimization strategies
The Ion Proton platform allows to perform whole exome sequencing (WES) at low cost, providing rapid turnaround time and great flexibility. Products for WES on Ion Proton system include the AmpliSeq Exome kit and the recently introduced HiQ sequencing chemistry. Here, we used gold standard variants f...
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| Опубликовано в: : | Hum Genet |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Berlin Heidelberg
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835520/ https://ncbi.nlm.nih.gov/pubmed/27003585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1656-8 |
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