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Amplicon-based semiconductor sequencing of human exomes: performance evaluation and optimization strategies

The Ion Proton platform allows to perform whole exome sequencing (WES) at low cost, providing rapid turnaround time and great flexibility. Products for WES on Ion Proton system include the AmpliSeq Exome kit and the recently introduced HiQ sequencing chemistry. Here, we used gold standard variants f...

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Detalhes bibliográficos
Publicado no:Hum Genet
Main Authors: Damiati, E., Borsani, G., Giacopuzzi, Edoardo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835520/
https://ncbi.nlm.nih.gov/pubmed/27003585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1656-8
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