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Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology

Mesenchymal stem (or stromal) cells (MSCs) have been used in more than 400 clinical trials for the treatment of various diseases. The clinical benefit and reproducibility of results, however, remain extremely variable. During the in vitro expansion phase, which is necessary to achieve clinically rel...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Selich, Anton, Daudert, Jannik, Hass, Ralf, Philipp, Friederike, von Kaisenberg, Constantin, Paul, Gabi, Cornils, Kerstin, Fehse, Boris, Rittinghausen, Susanne, Schambach, Axel, Rothe, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835246/
https://ncbi.nlm.nih.gov/pubmed/27034413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0176
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