Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis

Silica dust mainly attacks alveolar macrophages (AMs) and increases the apoptosis of AMs in silicosis patients. However, it is still unclear whether autophagy is affected. Autophagy mainly has defensive functions in response to stress, contributing to cell survival in adverse conditions, and convers...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Chen, Shi, Yuan, Juxiang, Yao, Sanqiao, Jin, Yulan, Chen, Gang, Tian, Wei, Xi, Jinkun, Xu, Zhelong, Weng, Dong, Chen, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Translational Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835201/
https://ncbi.nlm.nih.gov/pubmed/26553601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1109765
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