Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis

Silica dust mainly attacks alveolar macrophages (AMs) and increases the apoptosis of AMs in silicosis patients. However, it is still unclear whether autophagy is affected. Autophagy mainly has defensive functions in response to stress, contributing to cell survival in adverse conditions, and convers...

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Veröffentlicht in:Autophagy
Hauptverfasser: Chen, Shi, Yuan, Juxiang, Yao, Sanqiao, Jin, Yulan, Chen, Gang, Tian, Wei, Xi, Jinkun, Xu, Zhelong, Weng, Dong, Chen, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Translational Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835201/
https://ncbi.nlm.nih.gov/pubmed/26553601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1109765
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