Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice

Autophagy is a self-degradative process responsible for the clearance of damaged or unnecessary cellular components. We have previously found that persistence of dysfunctional organelles due to autophagy failure is a key event in the pathogenesis of COL6/collagen VI-related myopathies, and have demo...

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Vydáno v:Autophagy
Hlavní autoři: Chrisam, Martina, Pirozzi, Marinella, Castagnaro, Silvia, Blaauw, Bert, Polishchuck, Roman, Cecconi, Francesco, Grumati, Paolo, Bonaldo, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Basic Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835186/
https://ncbi.nlm.nih.gov/pubmed/26565691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1108508
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