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High Risk of Colorectal and Endometrial Cancer in Ashkenazi families with the MSH2 A636P founder mutation
BACKGROUND & AIMS: The MSH2 A636P mutation is a founder mutation in Ashkenazi Jews that causes Lynch syndrome with a prevalence of 0.4%–0.7%. Estimates of age-specific cumulative risk and lifetime risk for colorectal cancer (CRC) and endometrial cancer (EC) specific to carriers of this mutation...
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| Udgivet i: | Gastroenterology |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835182/ https://ncbi.nlm.nih.gov/pubmed/21419771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.02.071 |
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