Prenatal Ethanol Exposure Up-Regulates the Cholesterol Transporters ATP-Binding Cassette A1 and G1 and Reduces Cholesterol Levels in the Developing Rat Brain

Aims: Cholesterol plays a pivotal role in many aspects of brain development; reduced cholesterol levels during brain development, as a consequence of genetic defects in cholesterol biosynthesis, leads to severe brain damage, including microcephaly and mental retardation, both of which are also hallm...

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Publicado en:Alcohol Alcohol
Autores principales: Zhou, Chunyan, Chen, Jing, Zhang, Xiaolu, Costa, Lucio G., Guizzetti, Marina
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
Metabolic
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834908/
https://ncbi.nlm.nih.gov/pubmed/25081040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agu049
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