Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation

The pathogenesis of heart failure with a preserved ejection fraction (HFpEF) is unclear. Myocardial fibrosis, inflammation, and cardiac hypertrophy have been suggested to contribute to the pathogenesis of HFpEF. Cardiosphere-derived cells (CDCs) are heart-derived cell products with antifibrotic and...

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Foilsithe in:JACC Basic Transl Sci
Main Authors: Gallet, Romain, de Couto, Geoffrey, Simsolo, Eli, Valle, Jackelyn, Sun, Baiming, Liu, Weixin, Tseliou, Eleni, Zile, Michael R., Marbán, Eduardo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2016
Ábhair:
PRE-CLINICAL RESEARCH
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834906/
https://ncbi.nlm.nih.gov/pubmed/27104217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2016.01.003
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