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Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes.

The 5' flanking region of the mouse renin genes (Ren-1d and Ren-2d) contains two motifs that are homologous to known negative regulatory elements (NREs). Ren-2d has a 150-base-pair (bp) insertion 5' to the upstream putative NRE (NRE-1), which is lacking in Ren-1d. We tested the functionali...

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Main Authors: Barrett, G, Horiuchi, M, Paul, M, Pratt, R E, Nakamura, N, Dzau, V J
格式: Artigo
語言:Inglês
出版: 1992
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC48349/
https://ncbi.nlm.nih.gov/pubmed/1736303
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