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In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer.

DBA/2J mouse contains two renin gene loci (Ren1d and Ren2d). Ren2d but not Ren1d is expressed in submandibular gland (SMG) while both are expressed in the kidney. Based on vitro studies, we have postulated that a negative regulatory element (NRE) in the renin gene promoter is involved in its tissue-...

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Autors principals: Yamada, T, Horiuchi, M, Morishita, R, Zhang, L, Pratt, R E, Dzau, V J
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC185743/
https://ncbi.nlm.nih.gov/pubmed/7657796
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