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In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer.

DBA/2J mouse contains two renin gene loci (Ren1d and Ren2d). Ren2d but not Ren1d is expressed in submandibular gland (SMG) while both are expressed in the kidney. Based on vitro studies, we have postulated that a negative regulatory element (NRE) in the renin gene promoter is involved in its tissue-...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Yamada, T, Horiuchi, M, Morishita, R, Zhang, L, Pratt, R E, Dzau, V J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118156
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