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Deletion of OTX2 in neural ectoderm delays anterior pituitary development
OTX2 is a homeodomain transcription factor that is necessary for normal head development in mouse and man. Heterozygosity for loss-of-function alleles causes an incompletely penetrant, haploinsufficiency disorder. Affected individuals exhibit a spectrum of features that range from developmental defe...
Guardado en:
| Publicado en: | Hum Mol Genet |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834879/ https://ncbi.nlm.nih.gov/pubmed/25315894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu506 |
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