Pitx2 Deletion in Pituitary Gonadotropes is Compatible with Gonadal Development, Puberty and Fertility

This report introduces a gonadotrope-specific cre transgenic mouse capable of ablating floxed genes in mature pituitary gonadotropes. Initial analysis of this transgenic line, Tg(Lhb-cre)1Sac, reveals expression is limited to the pituitary cells that produce luteinizing hormone beta, beginning appro...

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Bibliographic Details
Main Authors: Charles, Michael A., Mortensen, Amanda H., Potok, Mary Anne, Camper, Sally A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923441/
https://ncbi.nlm.nih.gov/pubmed/18802953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20398
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