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Metabolism of AM404 From Acetaminophen at Human Therapeutic Dosages in the Rat Brain
BACKGROUND: Acetaminophen, an analgesic and antipyretic drug, has been used clinically for more than a century. Previous studies showed that acetaminophen undergoes metabolic transformations to form an analgesic compound, N-(4-hydroxyphenyl) arachidonamide (AM404), in the rodent brain. However, thes...
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Vydáno v: | Anesth Pain Med |
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Hlavní autoři: | , , , , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Kowsar
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834746/ https://ncbi.nlm.nih.gov/pubmed/27110534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/aapm.32873 |
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