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Discovery of Potent and Selective Agonists of δ Opioid Receptor by Revisiting the “Message-Address” Concept

[Image: see text] The classic “message-address” concept was proposed to address the binding of endogenous peptides to the opioid receptors and was later successfully applied in the discovery of the first nonpeptide δ opioid receptor (DOR) antagonist naltrindole. By revisiting this concept, and based...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Shen, Qing, Qian, Yuanyuan, Huang, Xiaoqin, Xu, Xuejun, Li, Wei, Liu, Jinggen, Fu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834657/
https://ncbi.nlm.nih.gov/pubmed/27096047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00423
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