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Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene

We have developed retroviral replicating vectors (RRV) derived from Moloney murine gammaretrovirus with an amphotropic envelope and an encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES)-transgene cassette downstream of the env gene. During long-term (180 days) replication of the v...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Hum Gene Ther Methods
المؤلفون الرئيسيون:	Lin, Amy H., Liu, Yanzheng, Burrascano, Cynthia, Cunanan, Kathrina, Logg, Christopher R., Robbins, Joan M., Kasahara, Noriyuki, Gruber, Harry, Ibañez, Carlos, Jolly, Douglas J.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Mary Ann Liebert, Inc. 2016
الموضوعات:	Research Articles
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4834527/ https://ncbi.nlm.nih.gov/pubmed/26918465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2015.131
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Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene

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