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Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene
We have developed retroviral replicating vectors (RRV) derived from Moloney murine gammaretrovirus with an amphotropic envelope and an encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES)-transgene cassette downstream of the env gene. During long-term (180 days) replication of the v...
Zapisane w:
Wydane w: | Hum Gene Ther Methods |
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Główni autorzy: | , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Mary Ann Liebert, Inc.
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834527/ https://ncbi.nlm.nih.gov/pubmed/26918465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2015.131 |
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