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Characterization of a nose-only inhaled phosgene acute lung injury mouse model

CONTEXT: Phosgene’s primary mode of action is as a pulmonary irritant characterized by its early latent phase where life-threatening, non-cardiogenic pulmonary edema is typically observed 6–24 h post-exposure. OBJECTIVE: To develop an inhaled phosgene acute lung injury (ALI) model in C57BL/6 mice th...

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Bibliographic Details
Published in:Inhal Toxicol
Main Authors: Plahovinsak, Jennifer L., Perry, Mark R., Knostman, Katherine A., Segal, Robert, Babin, Michael C.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834457/
https://ncbi.nlm.nih.gov/pubmed/26671199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08958378.2015.1117549
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