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Reconstructed Metabolic Network Models Predict Flux-Level Metabolic Reprogramming in Glioblastoma

Developments in genome scale metabolic modeling techniques and omics technologies have enabled the reconstruction of context-specific metabolic models. In this study, glioblastoma multiforme (GBM), one of the most common and aggressive malignant brain tumors, is investigated by mapping GBM gene expr...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Özcan, Emrah, Çakır, Tunahan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834348/
https://ncbi.nlm.nih.gov/pubmed/27147948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00156
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