Ursodeoxycholic acid inhibits Clostridium difficile spore germination and vegetative growth, and prevents recurrence of ileal pouchitis associated with the infection

GOALS: Test whether ursodeoxycholic acid is inhibitory to Clostridium difficile and can be used in the treatment of C. difficile associated ileal pouchitis. BACKGROUND: Restoration of secondary bile metabolism may be the key mechanism for fecal microbiota transplantation (FMT) in treating recurrent...

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Publicado no:J Clin Gastroenterol
Main Authors: Weingarden, Alexa R., Chen, Chi, Zhang, Ningning, Graiziger, Carolyn T., Dosa, Peter I., Steer, Clifford J., Shaughnessy, Megan K., Johnson, James R., Sadowsky, Michael. J., Khoruts, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834285/
https://ncbi.nlm.nih.gov/pubmed/26485102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MCG.0000000000000427
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