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The Virtual Screening of the Drug Protein with a Few Crystal Structures Based on the Adaboost-SVM

Using the theory of machine learning to assist the virtual screening (VS) has been an effective plan. However, the quality of the training set may reduce because of mixing with the wrong docking poses and it will affect the screening efficiencies. To solve this problem, we present a method using the...

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Detalhes bibliográficos
Publicado no:Comput Math Methods Med
Main Authors: Wang, Meng-yu, Li, Peng, Qiao, Pei-li
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834164/
https://ncbi.nlm.nih.gov/pubmed/27127534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4809831
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