OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells

The reprogramming factors OCT4, SOX2, KLF4, and MYC (OSKM) can reactivate the pluripotency network in terminally differentiated cells, but also regulate expression of non-pluripotency genes in other contexts, such as the mouse primitive endoderm. The primitive endoderm is an extraembryonic lineage e...

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Publicado en:Stem Cell Reports
Main Authors: Parenti, Anthony, Halbisen, Michael A., Wang, Kai, Latham, Keith, Ralston, Amy
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834035/
https://ncbi.nlm.nih.gov/pubmed/26947975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.02.003
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