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Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells

Evolutionally conserved Nanos RNA-binding proteins play crucial roles in germ cell development. While a mammalian Nanos family protein, NANOS2, is required for sexual differentiation of male (XY) germ cells in mice, the underlying mechanisms and the identities of its target RNAs in vivo remain elusi...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Kato, Yuzuru, Katsuki, Takeo, Kokubo, Hiroki, Masuda, Aki, Saga, Yumiko
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833867/
https://ncbi.nlm.nih.gov/pubmed/27072294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11272
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