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Nanos2 suppresses meiosis and promotes male germ cell differentiation
In mouse fetal gonads, retinoic acid (RA) induces meiosis in the female germ cells, whereas the male germ cells never enter meiosis due to Cyp26b1-mediated RA metabolism. We show here that Nanos2 plays critical roles in the differentiation of male germ cells. We find that Nanos2 maintains the suppre...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238665/ https://ncbi.nlm.nih.gov/pubmed/18281459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1612708 |
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