Llwytho...

Nanos2 suppresses meiosis and promotes male germ cell differentiation

In mouse fetal gonads, retinoic acid (RA) induces meiosis in the female germ cells, whereas the male germ cells never enter meiosis due to Cyp26b1-mediated RA metabolism. We show here that Nanos2 plays critical roles in the differentiation of male germ cells. We find that Nanos2 maintains the suppre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Suzuki, Atsushi, Saga, Yumiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238665/
https://ncbi.nlm.nih.gov/pubmed/18281459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1612708
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