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The dynamic organization of fungal acetyl-CoA carboxylase

Acetyl-CoA carboxylases (ACCs) catalyse the committed step in fatty-acid biosynthesis: the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. They are important regulatory hubs for metabolic control and relevant drug targets for the treatment of the metabolic syndrome and cancer. Eukaryotic A...

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Publicat a:Nat Commun
Autors principals: Hunkeler, Moritz, Stuttfeld, Edward, Hagmann, Anna, Imseng, Stefan, Maier, Timm
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833862/
https://ncbi.nlm.nih.gov/pubmed/27073141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11196
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