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Effect of Oxidative Damage on the Stability and Dimerization of Superoxide Dismutase 1

During their life cycle, proteins are subject to different modifications involving reactive oxygen species. Such oxidative damage to proteins may lead to the formation of insoluble aggregates and cytotoxicity and is associated with age-related disorders including neurodegenerative diseases, cancer,...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Petrov, Drazen, Daura, Xavier, Zagrovic, Bojan
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833831/
https://ncbi.nlm.nih.gov/pubmed/27074676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.02.037
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