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Cloning, expression and purification of the factor H binding protein and its interaction with factor H

BACKGROUND AND OBJECTIVE: Neisseria meningitidis is a leading cause of meningitis and sepsis worldwide. The factor H binding protein (fHBP) is a key virulence factor of Neisseria meningitidis that is able to selectively bind to human factor H, the key regulator of the alternative complement pathway,...

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Veröffentlicht in:Iran J Microbiol
Hauptverfasser: Yarian, Fatemeh, Bandehpour, Mojgan, Seyed, Negar, Kazemi, Bahram
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tehran University of Medical Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833738/
https://ncbi.nlm.nih.gov/pubmed/27092222
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