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Molecular Cloning, Expression and Enzymatic Assay of Pteridine Reductase 1 from Iranian Lizard Leishmania

Background: Currently, there are no effective vaccines against leishmaniasis, and treatment using pentavalent antimonial drugs is occasionally effective and often toxic for patients. The PTR1 enzyme, which causes antifolate drug resistance in Leishmania parasites encoded by gene pteridine reductase...

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Detalhes bibliográficos
Main Authors: Kazemi, Bahram, Tohidi, Farideh, Bandehpour, Mojgan, Yarian, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: Pasteur Institute of Iran 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904060/
https://ncbi.nlm.nih.gov/pubmed/21079660
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