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mutation3D: cancer gene prediction through atomic clustering of coding variants in the structural proteome

A new algorithm and web server, mutation3D (http://mutation3d.org), proposes driver genes in cancer by identifying clusters of amino acid substitutions within tertiary protein structures. We demonstrate the feasibility of using a 3D clustering approach to implicate proteins in cancer based on explor...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Meyer, Michael J., Lapcevic, Ryan, Romero, Alfonso E., Yoon, Mark, Das, Jishnu, Beltrán, Juan Felipe, Mort, Matthew, Stenson, Peter D., Cooper, David N., Paccanaro, Alberto, Yu, Haiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833594/
https://ncbi.nlm.nih.gov/pubmed/26841357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22963
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