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iRegNet3D: three-dimensional integrated regulatory network for the genomic analysis of coding and non-coding disease mutations

The mechanistic details of most disease-causing mutations remain poorly explored within the context of regulatory networks. We present a high-resolution three-dimensional integrated regulatory network (iRegNet3D) in the form of a web tool, where we resolve the interfaces of all known transcription f...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Liang, Siqi, Tippens, Nathaniel D., Zhou, Yaoda, Mort, Matthew, Stenson, Peter D., Cooper, David N., Yu, Haiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241969/
https://ncbi.nlm.nih.gov/pubmed/28100260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1138-2
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