ALDOSTERONE-INDUCED VASCULAR REMODELING AND ENDOTHELIAL DYSFUNCTION REQUIRE FUNCTIONAL ANGIOTENSIN TYPE 1a RECEPTORS

We investigated the role of angiotensin type 1a receptors (AGTR1a) in vascular injury induced by aldosterone activation of mineralocorticoid receptors (MR) in Agtr1a(−/−) and wild-type mice infused with aldosterone for 14 days while receiving 1% NaCl in drinking water. Aldosterone increased systolic...

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Pubblicato in:Hypertension
Autori principali: Briet, Marie, Barhoumi, Tlili, Mian, Muhammad Oneeb Rehman, Coelho, Suellen C., Ouerd, Sofiane, Rautureau, Yohann, Coffman, Thomas M., Paradis, Pierre, Schiffrin, Ernesto L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833572/
https://ncbi.nlm.nih.gov/pubmed/27045029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.07074
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