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Age- and hypertension-associated protein aggregates in mouse heart have similar proteomic profiles

Neurodegenerative diseases are largely defined by protein aggregates in affected tissues. Aggregates contain some shared components as well as proteins thought to be specific for each disease. Aggregation has not previously been reported in the normal, aging heart or the hypertensive heart. Detergen...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Ayyadevara, Srinivas, Mercanti, Federico, Wang, Xianwei, Mackintosh, Samuel G., Tackett, Alan J., Prayaga, Sastry V. S., Romeo, Francesco, Shmookler Reis, Robert J., Mehta, Jawahar L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833546/
https://ncbi.nlm.nih.gov/pubmed/26975704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06849
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