Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa

Most Retinitis Pigmentosa (RP) mutations arise in rod photoreceptor genes, leading to diminished peripheral and nightime vision. Using a pig model of autosomal-dominant RP, we show glucose becomes sequestered in the retinal pigment epithelium (RPE), and thus is not transported to photoreceptors. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Wang, Wei, Lee, Sang Joon, Scott, Patrick A., Lu, Xiaoqin, Emery, Douglas, Liu, Yongqin, Ezashi, Toshihiko, Roberts, Michael R., Ross, Jason W., Kaplan, Henry J., Dean, Douglas C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833509/
https://ncbi.nlm.nih.gov/pubmed/27050517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.022
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